Prevention, Longevity & Embracing Natural Aging

Scientific article: https://www.nature.com/articles/s41467-026-75141-2 Revel Pharmaceuticals, a spin out from SENS years ago. Also happy to see...

Research found that 1.5 hours of weekly strength training lowers the risk of death. Personal trainers share the best exercises to try.

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A recent study found that older adults who take a daily multivitamin may slow their biological aging by up to 4 months. The researchers note that multivitamins don't add years to life span, but they may benefit long-term health.

A squeeze of the hand, a glimpse of the brain.

Colorectal cancer is now the leading cause of death due to cancer for Americans under 50, according to a new report from the American Cancer Society (ACS). The report found that colon cancer death rates are rising annually, while deaths from other major cancers have declined.

Scientists at Stanford Medicine have discovered a treatment that can reverse cartilage loss in aging joints and even prevent arthritis after knee injuries. By blocking a protein linked to aging, the therapy restored healthy, shock-absorbing cartilage in old mice and injured joints, dramatically improving movement and joint function. Human cartilage samples from knee replacement surgeries also began regenerating when exposed to the treatment.

All forms of exercise help you live longer, but some activities come with extra benefits.

Global cancer cases have surged dramatically, doubling since 1990 and reaching 18.5 million new diagnoses in 2023. Deaths have also climbed to over 10 million a year, with the steepest increases hitting low- and middle-income countries. Without urgent action, researchers project more than 30 million new cases annually by 2050. Alarmingly, around four in ten cancer deaths are tied to preventable risks such as smoking, poor diet, and high blood sugar.

An analysis of Framingham Heart Study data reveals that accelerated DNA methylation aging predicts worse performance on the digital Clock Drawing Test nearly a decade later.

Eating full-fat cheese and cream may be associated with a lower risk of dementia, according to a large study that tracked people for more than 25 years. Those who consumed higher amounts of these foods developed dementia less often than those who ate little or none. Interestingly, low-fat dairy products did not show the same pattern. Researchers caution that the findings show an association, not cause and effect.

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Three intriguing research studies suggest inexpensive ways to reduce the risk of dementia and improve lifespan without medications.

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Scientists discovered that more muscle and less hidden abdominal fat are linked to a younger biological brain age. Deep visceral fat appeared to accelerate brain aging, while muscle mass offered a protective effect.

This is one of the biggest predictors of brain health—do you have it?

Hydrocortisone and testosterone are just two of 13 drugs and supplements that could lessen the impact of genes that accelerate brain ageing

New research from Australia overturns the old idea that exercise “uses up” heartbeats. It shows that fitter people actually use fewer total heartbeats each day thanks to their lower resting heart rates, even when accounting for workouts. Athletes’ hearts beat around 10% less daily, saving over 11,000 beats per day compared to sedentary people. This efficiency not only signals cardiovascular fitness but also translates to longer life expectancy and lower disease risk.

Accumulating steps during bouts of at least 15 minutes was associated with a lower risk of dying over nearly a decade of follow-up.

Life is finite. Make it count! See how habits and biology affect your lifespan.