A new study suggests that depression after traumatic brain injury (TBI) could be a clinically distinct disorder rather than traditional major depressive disorder, with implications for patient treatment.

All antidepressants were more efficacious than placebo in adults with major depressive disorder. Smaller differences between active drugs were found when placebo-controlled trials were included in the analysis, whereas there was more variability in efficacy and acceptability in head-to-head trials. These results should serve evidence-based practice and inform patients, physicians, guideline developers, and policy makers on the relative merits of the different antidepressants.

Understanding depression as an altered state of consciousness, like a dream or drug trip, could help people awaken from it

Common wisdom says depression starts in the mind with distorted thinking. But newer models suggest depression starts when the body initiates a defense strategy to help us survive.

There is a spectrum of feelings and thoughts, called suicidal ideation, that many people experience, and it’s not the same as planning out a death. Here’s what people say it feels like and how they want to receive help.

Depression with melancholic features is defined by a complete loss of pleasure and reactivity. We look at how melancholic depression compares to other types.

Here's what experts and research say about the different ways depression symptoms may occur and other conditions that may also involve depression symptoms.

It is crucial to first and foremost see anxiety and depression as symptoms of unmet needs for relational value, rather than diseases of the brain.

6 answers to question "How to get rid of post alcohol depression ?"

You're definitely not alone in your post-partying blues.

These four “natural” therapies for depression have rigorous, peer-reviewed scientific studies to support their use.

There are three types of depression determined by unusual brain activity patterns and childhood trauma, says a new study published in Scientific Reports. Anti-depressants didn’t work on one type of depression.

This is so spot-on.

The one symptom of depression you probably don’t know about, and one of the hardest ones to deal with, is loneliness.

Hey, Captain and Co. I spent the past two years of my life being really depressed (and, honestly, who knows how long before that — I was only diagnosed last year, but I’ve felt pretty a…

In honor of World Mental Health Day, let's talk mental health solutions.

Approximately two in five adults (39 percent) who have experienced major depression are able to achieve complete mental health. Researchers consider complete mental health as occurring when people achieve almost daily happiness or life satisfaction, positive social and psychological well-being, and are also free of depression, anxiety, suicidal thoughts and substance abuse for at least one full year.

Living with depression is hard. Period. But you’re doing the best you can. So, the next time you have a day where it feels like depression and your bed are winning, be gentle with yourself — and consider these tips.