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Fish oil supplements successfully delivered omega-3s to the brain, but a two-year study found no meaningful benefits for memory, cognition, or Alzheimer’s-related brain changes. The results challenge the idea that fish oil pills can help prevent Alzheimer’s and shift attention toward overall diet and lifestyle instead.

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A persistent viral infection may explain the elusive cause of multiple sclerosis. Researchers found that immune cells abundant in patients' spinal fluid are primed to attack the Epstein-Barr virus, potentially triggering collateral nerve damage.

Over 7 years, hearing aid prescription did not improve cognition but was associated with a significant reduction in the risk for dementia in older adults with moderate hearing loss.

Findings could create new opportunities to treat and study neurodegenerative diseasesScientists discovered that sugar metabolism plays a surprising role in whether injured neurons collapse or cling to life. By activating internal protective programs, certain metabolic changes can temporarily slow neurodegeneration—hinting at new ways to help the brain defend itself.

Exposure to common environmental chemicals, especially in combination, is linked to an increased risk of multiple sclerosis.

Researchers discovered that clogged brain “drains” show up early in people at risk of Alzheimer’s disease. These blockages, easily seen on standard MRI scans, are tied to toxic protein buildup linked to memory loss and cognitive decline. In some cases, they may signal Alzheimer’s earlier than other commonly used brain markers. This could help physicians detect the disease earlier, before irreversible damage sets in.

For more than a century, people have considered Alzheimer's disease (AD) an irreversible illness. Consequently, research has focused on preventing or slowing it, rather than recovery. Despite billions of dollars spent on decades of research, there has never been a clinical trial of any drug to reverse and recover from AD.

High inflammation may disrupt the brain's reward system in Indigenous adults with depression, according to new neuroscience research.

Obesity accelerates the rise of Alzheimer’s-related blood biomarkers far more rapidly than previously recognized. Long-term imaging and plasma data show that obese individuals experience much faster increases in proteins linked to neurodegeneration and amyloid buildup. Surprisingly, blood tests detected these changes earlier than PET scans. The results point to obesity as a major, modifiable contributor to Alzheimer’s progression.

The brain’s waste disposal system has hidden pathways. A new study reveals a previously unknown route, changing our map of how the brain stays clean and offering new clues for understanding neurological disease.

Researchers discovered that altering the body’s natural rhythm can help protect the brain from Alzheimer’s damage. By turning off a circadian protein in mice, they raised NAD+ levels and reduced harmful tau buildup. The findings suggest that adjusting the body’s clock may one day help prevent neurodegeneration.

A multinational analysis and Swedish registry data show higher dementia mortality after age 80 and a twofold dementia risk in those with type 1 diabetes.

Researchers have finally seen and measured the tiny alpha-synuclein oligomers that may ignite Parkinson’s disease. With the ultra-sensitive ASA-PD imaging method, they captured these clusters in brain tissue, finding larger and more numerous versions in patients with Parkinson’s. The discovery could mark a turning point in diagnosing and treating the disease, revealing the first visible signs long before symptoms appear.

A long-term Australian study found that calcium supplements do not raise dementia risk in older women, countering previous fears. The research followed more than 1,400 participants for nearly 15 years and revealed no harmful cognitive effects. Scientists say these results should reassure those using calcium to prevent osteoporosis, though more research is needed across broader populations.

New research from Houston Methodist reveals how obesity may directly drive Alzheimer’s disease. Scientists discovered that tiny messengers released by fat tissue, called extracellular vesicles, can carry harmful signals that accelerate the buildup of amyloid-β plaques in the brain. These vesicles even cross the blood–brain barrier, making them powerful but dangerous connectors between body fat and brain health.

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The Mediterranean diet is linked to reduced Alzheimer’s risk, particularly in individuals with the highest risk for the disease.

Overactivation of dopamine neurons may directly drive their death, explaining why movement-controlling brain cells degenerate in Parkinson’s. Mice with chronically stimulated neurons showed the same selective damage seen in patients, along with molecular stress responses. Targeting this overactivity could help slow disease progression.

Alzheimer’s disease is traditionally seen as a brain disorder, but new research using fruit flies reveals that it also affects organs and tissues throughout the body.