Brain Damage

"Study shows impaired energy metabolism in the brains of people with post-COVID" Brain fog, poor concentration and slowed thinking in Long COVID patients are linked to altered brain energy metabolism, with MRI studies showing changes that correlate with worse cognitive test performance.

Brain scans before and after infection showed more loss of gray matter and tissue damage, mostly in areas related to smell, in people who had Covid than in those who did not.

Massive increases in Alzheimers Dementia in over 65s if they had Covid massive new study shows: Loss of sense of smell are the first warning signs of both Alzheimer's and Parkinsons...

People who had COVID-19 are at higher risk for a host of brain injuries a year later compared with people who were never infected by the coronavirus, a finding that could affect millions of Americans, U.S. researchers reported on Thursday.

Individuals with COVID-19 are at an increased risk for an array of neurologic disorders at 12 months, even in those who were not hospitalized during the acute phase of the infection.

COVID-19 can result in neurological manifestations and animal models could provide insights into the mechanisms. Here, the authors describe neuroinflammation, microhemorrhages and brain hypoxia in SARS-CoV-2 infected non-human primates, including in animals that don’t develop severe respiratory disease.

The neurological deficits caused by COVID-19, which were first reported in the early months of 2020, continue to intrigue neurologists and health-care professionals worldwide. As two new studies highlight, these manifestations are frequent and are expected to increase the burden of morbidity and mortality in the acute and chronic phases of COVID-19.

An infectious etiology of Alzheimer’s disease has been postulated for decades. It remains unknown whether SARS-CoV-2 viral infection is associated with increase...

Viruses like HSV-1 and SARS-CoV-2 might trigger Alzheimer’s disease.

Professor Massimo Hilliard and Dr Ramon Martinez-Marmol have discovered viruses such as SARS-CoV-2 can cause brain cells to fuse, initiating malfunctions that lead to chronic neurological symptoms.

Purpose Although COVID-19 typically presents with respiratory symptoms, it can also lead to severe neurological manifestations in children. While case reports of COVID-19–associated encephalopathy (including acute necrotizing encephalopathy) have increasingly appeared, gaps remain regarding optimal management strategies and outcome predictors for children with rapid-onset neurological decline. This report aims to underscore the critical need for standardized clinical approaches to severe pediatric COVID-19–related encephalopathy. Methods In this case report, We detail the case of an 8-year-old girl who presented with fever, rash, headache, and recurrent seizures. Her diagnostic workup included polymerase chain reaction (PCR) testing for SARS-CoV-2 and a range of neurological assessments: contrast-enhanced computed tomography (CT) to evaluate structural changes, transcranial Doppler ultrasound to assess intracranial hemodynamics, and electroencephalography (EEG) to monitor electrical activity. Intensive therapeutic measures—encompassing mechanical ventilation, hemodynamic support, antimicrobial agents, and corticosteroids—were initiated. In addition, a targeted narrative literature review of pediatric COVID-19–associated neurological complications was conducted to contextualize this presentation. Results The patient tested positive for COVID-19;imaging revealed brain edem, and EEG suggested brain death. Despite aggressive critical care interventions, her condition did not improve, ultimately resulting in brain death. Our review of current literature revealed several reported instances of acute necrotizing encephalopathy in pediatric COVID-19, highlighting a growing body of evidence on the potential for severe central nervous system sequelae. Conclusion This case highlights the importance of early recognition and close neurological surveillance in pediatric patients with COVID-19. Although accumulating evidence describes COVID-19–related neurological complications such as acute necrotizing encephalopathy, uncertainties persist regarding definitive treatment protocols and long-term outcomes. Greater understanding of the underlying mechanisms and standardized management pathways is imperative to improve prognosis in this vulnerable population. Clinical trial Not applicable.

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How Covid-19 fulfils the Bradford Hill criteria for causation and raises your lifetime risk of dementia from 1% to 1.5%.

People who have a COVID-19 infection are more likely to develop seizures or epilepsy within the next six months than people who have an influenza infection, according to a new study.

Cognitive impairment as a result of severe COVID-19 is similar to that sustained between 50 and 70 years of age and is the equivalent to losing 10 IQ points,

Recent brain imaging shows the disease can cause physical changes equivalent to a decade of aging and trigger problems with attention and memory. Exactly why is still a mystery.

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COVID-19 does not just affect the respiratory system, but also significantly alters the brain in people who have fully recovered from the infectious